CYP1A2 / Unconjugated /

Product Details
Supplier St John's Laboratory
Catalog #: STJ23317-50μl (View supplier product page)
Size 50 μl
Price $248.00
Antigen CYP1A2
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Mouse, Rat
Applications WB
Description Rabbit polyclonal to CYP1A2
About CYP1A2 and Purified
CYP1A2 This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra