RBM8A / Unconjugated /

Product Details
Supplier St John's Laboratory
Catalog #: STJ111547-100μl (View supplier product page)
Size 100 μl
Price $356.50
Antigen RBM8A
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Mouse
Applications WB
Description Rabbit polyclonal to RBM8A
About RBM8A and Purified
RBM8A This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013]
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Purified Excitation and Emission Spectra