FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP1-82633 (View supplier product page)
	Size	0.1 ml
	Price	$519.00
	Antigen	NSD2
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human
	Applications	IHC, ICC/IF, IHC-P, WB
	Description	Specificity of human WHSC1 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

	NSD2	This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. [provided by RefSeq, Jul 2008]

		Immunocytochemistry/Immunofluorescence: WHSC1 Antibody [NBP1-82633] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli.
		Immunohistochemistry-Paraffin: WHSC1 Antibody [NBP1-82633] - Staining of human oral mucosa shows strong nuclear positivity in squamous epithelial cells.
		Immunohistochemistry-Paraffin: WHSC1 Antibody [NBP1-82633] - Staining in human testis and liver tissues using anti-NSD2 antibody. Corresponding NSD2 RNA-seq data are presented for the same tissues.
		Immunohistochemistry-Paraffin: WHSC1 Antibody [NBP1-82633] - Staining of human liver shows low expression as expected.
		Immunohistochemistry-Paraffin: WHSC1 Antibody [NBP1-82633] - Staining of human testis shows high expression.