VEGFR1 / Janelia Fluor 549 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-527JF549 (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen VEGFR1
Clone
Host Rabbit
Isotype IgG
Conjugate Janelia Fluor 549
Target Species Human
Applications IHC, ICC/IF, IHC-P
Description This antibody targets VEGFR-1 but has significant cross-reactivity with the VEGFR-2 protein.
About VEGFR1 and Janelia Fluor 549
VEGFR1 This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
Janelia Fluor 549 Janelia Fluor® 549 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 549 has an excitation peak at 549 nm and an emission peak at 571 nm.
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Janelia Fluor 549 Excitation and Emission Spectra