Urokinase / DyLight 755 / OTI5H4

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-74793IR (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen Urokinase
Clone OTI5H4
Host Mouse
Isotype IgG2a
Conjugate DyLight 755
Target Species Human
Applications WB, IHC
Description Mouse u-Plasminogen Activator/Urokinase antibody [DyLight 755] detects Human
About Urokinase and DyLight 755
Urokinase This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra