Syntrophin alpha 1 / Alexa Fluor 700 / OTI1H10

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-74422AF700 (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen Syntrophin alpha 1
Clone OTI1H10
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 700
Target Species Canine, Human, Monkey, Rat
Applications WB, FC, ICC/IF
Description Mouse Syntrophin alpha 1 antibody [Alexa Fluor 700] detects Human, Rat, Canine, Monkey
About Syntrophin alpha 1 and Alexa Fluor 700
Syntrophin alpha 1 Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra