Sulfatase-2 / Janelia Fluor 549 / 2B4

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-36727JF549 (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen Sulfatase-2
Clone 2B4
Host Mouse
Isotype IgG1
Conjugate Janelia Fluor 549
Target Species Human, Mouse
Applications FC, IHC, IHC-P
Description Does not recognize human or mouse Sulfatase 1 or other family members.
About Sulfatase-2 and Janelia Fluor 549
Sulfatase-2 Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008]
Janelia Fluor 549 Janelia Fluor® 549 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 549 has an excitation peak at 549 nm and an emission peak at 571 nm.
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Janelia Fluor 549 Excitation and Emission Spectra