SNAP25 / Janelia Fluor 646 / OTI4G5

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-74245JF646 (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen SNAP25
Clone OTI4G5
Host Mouse
Isotype IgG2a
Conjugate Janelia Fluor 646
Target Species Human
Applications FC, IHC, ICC/IF
Description Mouse SNAP25 antibody [Janelia Fluor 646] detects Human
About SNAP25 and Janelia Fluor 646
SNAP25 Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Janelia Fluor 646 Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.
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Janelia Fluor 646 Excitation and Emission Spectra