SHP2 / HRP / OTI3F2

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-74173H (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen SHP2
Clone OTI3F2
Host Mouse
Isotype IgG2a
Conjugate HRP
Target Species Canine, Human
Applications WB
Description Mouse SHP-2/PTPN11 antibody [HRP] detects Human, Canine
About SHP2 and HRP
SHP2 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]
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HRP Excitation and Emission Spectra