RASSF1 / DyLight 755 / OTI2B11

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-73786IR (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen RASSF1
Clone OTI2B11
Host Mouse
Isotype IgG1
Conjugate DyLight 755
Target Species Human
Applications WB, FC, IHC, ICC/IF
Description Mouse RASSF1 antibody [DyLight 755] detects Human
About RASSF1 and DyLight 755
RASSF1 This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra