PUMA / Janelia Fluor 646 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB500-261JF646 (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen PUMA
Clone
Host Rabbit
Isotype IgG
Conjugate Janelia Fluor 646
Target Species Human
Applications ICC, IF
Description Rabbit PUMA antibody [Janelia Fluor 646] detects Human
About PUMA and Janelia Fluor 646
PUMA This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
Janelia Fluor 646 Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Janelia Fluor 646 Excitation and Emission Spectra