PBX1 / HRP / OTI1C11

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-73265H (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen PBX1
Clone OTI1C11
Host Mouse
Isotype IgG1
Conjugate HRP
Target Species Human
Applications WB, IHC
Description Mouse PBX1 antibody [HRP] detects Human
About PBX1 and HRP
PBX1 This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]
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HRP Excitation and Emission Spectra