p53 / DyLight 488 / OTI5E2

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-73200G (View supplier product page)
Size 0.1 ml
Price $689.00
Antigen p53
Clone OTI5E2
Host Mouse
Isotype IgG1
Conjugate DyLight 488
Target Species Human, Monkey, Mouse
Applications WB, FC, IHC, ICC/IF
Description Mouse p53 antibody [DyLight 488] detects Human, Mouse, Monkey
About p53 and DyLight 488
p53 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra