PGC-1 alpha / Biotin /

Citations: (2)
Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-04676B (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen PGC-1 alpha
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Goat, Hamster, Human, Mouse, Porcine, Rat, Squirrel
Applications WB, ICC/IF, IHC-P, IHC-Fr, IHC, Knockout Validated
About PGC-1 alpha and Biotin
PGC-1 alpha The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
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Biotin Excitation and Emission Spectra