MART-1 / Unconjugated / M2-7C10
MART-1 / Unconjugated / M2-7C10
Product Details
Supplier | Novus Biologicals, a Bio-Techne brand | |
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Catalog #: | NBP2-15197-20ug (View supplier product page) | |
Size | 20 ug | |
Price | $219.00 | |
Antigen | MART-1 | |
Clone | M2-7C10 | |
Host | Mouse | |
Isotype | IgG2b κ | |
Conjugate | Unconjugated | |
Target Species | Human, Mouse (Negative), Rat (Negative) | |
Applications | WB, FC, ELISA, ICC/IF, IP, IHC-P, IHC-Fr, IHC | |
Description | This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. |
About MART-1 and Purified
MART-1 | Located in endoplasmic reticulum membrane; melanosome; and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022] |
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Citations
Reviews & Ratings
Purified Excitation and Emission Spectra
$219.00
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