KvBeta1 / Janelia Fluor 646 / OTI7F12

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-71349JF646 (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen KvBeta1
Clone OTI7F12
Host Mouse
Isotype IgG1
Conjugate Janelia Fluor 646
Target Species Human
Applications FC, IHC, ICC/IF
Description Mouse KvBeta1 antibody reacts with Human [Janelia Fluor 646]
About KvBeta1 and Janelia Fluor 646
KvBeta1 Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq, Apr 2015]
Janelia Fluor 646 Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.
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Janelia Fluor 646 Excitation and Emission Spectra