CD321 / DyLight 350 / OTI3H3

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-71876UV (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen CD321
Clone OTI3H3
Host Mouse
Isotype IgG2b
Conjugate DyLight 350
Target Species Human
Applications WB, IHC, ICC/IF
Description Mouse JAM-A antibody [DyLight 350] reacts with Human
About CD321 and DyLight 350
CD321 Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra