IL-6 / Alexa Fluor 488 / OTI3G9

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-71027AF488 (View supplier product page)
Size 0.1 ml
Price $689.00
Antigen IL-6
Clone OTI3G9
Host Mouse
Isotype IgG2a
Conjugate Alexa Fluor 488
Target Species Human
Applications WB, IHC, ICC/IF
Description Mouse IL-6 antibody reacts with Human [Alexa Fluor 488]
About IL-6 and Alexa Fluor 488
IL-6 This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra