GCLC / DyLight 488 / OTI1A3

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-70830G (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen GCLC
Clone OTI1A3
Host Mouse
Isotype IgG1
Conjugate DyLight 488
Target Species Human, Monkey, Rat
Applications WB, IHC
About GCLC and DyLight 488
GCLC Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra