FKBP5 / Janelia Fluor 646 / OTI3E9

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-70742JF646 (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen FKBP5
Clone OTI3E9
Host Mouse
Isotype IgG1
Conjugate Janelia Fluor 646
Target Species Human
Applications IHC, ICC/IF
About FKBP5 and Janelia Fluor 646
FKBP5 The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
Janelia Fluor 646 Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.
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Janelia Fluor 646 Excitation and Emission Spectra