COCO / DyLight 755 / OTI2H3

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-72456IR (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen COCO
Clone OTI2H3
Host Mouse
Isotype IgG1
Conjugate DyLight 755
Target Species Human
Applications WB, FC, IHC
Description Mouse COCO/DAND5 antibody [DyLight 755] reacts with Human
About COCO and DyLight 755
COCO This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq, Jul 2008]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra