BLNK / Biotin / OTI4C9

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-71855B (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen BLNK
Clone OTI4C9
Host Mouse
Isotype IgG2b
Conjugate Biotin
Target Species Human
Applications WB, IHC
Description Mouse BLNK antibody [Biotin] reacts with Human
About BLNK and Biotin
BLNK This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
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Biotin Excitation and Emission Spectra