BLNK / Alexa Fluor 488 / OTI4C9

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-71855AF488 (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen BLNK
Clone OTI4C9
Host Mouse
Isotype IgG2b
Conjugate Alexa Fluor 488
Target Species Human
Applications WB, IHC
Description Mouse BLNK antibody [Alexa Fluor 488] reacts with Human
About BLNK and Alexa Fluor 488
BLNK This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra