ASC / DyLight 650 / OTI3E9

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-71853C (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen ASC
Clone OTI3E9
Host Mouse
Isotype IgG1
Conjugate DyLight 650
Target Species Human
Applications WB, FC, IHC
Description Mouse ASC/TMS1 antibody [DyLight 650] reacts with Human
About ASC and DyLight 650
ASC This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
DyLight 650 DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 650 Excitation and Emission Spectra