Argininosuccinate Lyase / DyLight 405 / OTI3D4

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-70213V (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen Argininosuccinate Lyase
Clone OTI3D4
Host Mouse
Isotype IgG2a
Conjugate DyLight 405
Target Species Human
Applications WB
About Argininosuccinate Lyase and DyLight 405
Argininosuccinate Lyase This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra