IKZF3 / Alexa Fluor 405 / OTI7E11

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-71698AF405 (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen IKZF3
Clone OTI7E11
Host Mouse
Isotype IgG2b
Conjugate Alexa Fluor 405
Target Species Human
Applications WB, IHC
Description Mouse Aiolos/IKZF3 antibody reacts with Human [Alexa Fluor 405]
About IKZF3 and Alexa Fluor 405
IKZF3 This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra