FluoroFinder

	Supplier	Miltenyi Biotec
	Catalog #:	130-120-198 (View supplier product page)
	Size	30 µg in 200 µL
	Price	$110.00
	Antigen	Siglec-H
	Clone	REAL248
	Host	cell line
	Isotype	IgG
	Conjugate	APC
	Target Species	Mouse
	Applications	FC
	Description	Clone REAL248 is an antibody fragment derived from the full Siglec-H antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. \| Clone REAL248 recognizes the mouse siglec-H antigen, a 34 kDa transmembrane protein of the Ig superfamily known as mouse sialic acid-binding immunoglobulin-like lectin. Siglec-H is specifically expressed on mouse plasmacytoid dendritic cells, a subset of CD11c+ dendritic cells detected at low frequency in all lymphoid tissues, peripheral blood, and some non-lymphoid tissues. Binding of antibodies to siglec-H inhibits type I interferon production, which can be induced in plasmacytoid dendritic cells by DNA and RNA viruses. \| The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

$110.00
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Siglec-H / APC / REAL248