FluoroFinder

	Supplier	Miltenyi Biotec
	Catalog #:	130-119-061 (View supplier product page)
	Size	150 µg in 1 mL
	Price	$240.00
	Antigen	NKG2A/C/E
	Clone	REA1100
	Host	Human
	Isotype	IgG1
	Conjugate	PE
	Target Species	Mouse
	Applications	FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
	Description	Clone REA1100 recognizes the mouse NKG2A, NKG2C, and NKG2E antigen on a subset of natural killer (NK) and NK-T cells in most mouse strains, for example, AKR/J, BALB/c, C3H/He,C57BL/6, CBA/J, DBA/1, FVB/N, 129/Sv, NOD, SWR, and most DBA/2 substrains, but not DBA/2J. The C-type lectin-like NKG2 receptors form heterodimers of CD94 and one of several NKG2 family members, i.e., NKG2A (CD159a), NKG2C (CD159c), or NKG2E. CD94/NKG2 receptors monitor classical class I expression indirectly by means of the recognition of classical class I signal peptides. These signal peptides are processed to a nonameric peptide called Qdm that is presented to CD94/NKG2+ NK cells by a non-classical MHC class I molecule called Qa-1. CD94/NKG2 receptors equip NK cells with the capacity to detect cells with abnormal MHC class I expression, such as often results from viral infection or transformation. \| Additional information: Clone REA1100 displays negligible binding to Fc receptors.

$240.00
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NKG2A/C/E / PE / REA1100