MICA/MICB / PE-Vio615 / REA1076

Citations: (3)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-118-831 (View supplier product page)
Size 100 tests in 200 µL
Price $355.00
Antigen MICA/MICB
Clone REA1076
Host Human
Isotype IgG1
Conjugate PE-Vio615
Target Species Human
Applications FC
Description Clone REA1076 recognizes MICA and MICB, which are transmembrane glycoproteins related to major histocompatibility complex (MHC) class I molecules. In contrast to other MHC class I proteins, MICA and MICB have no association with β2-microglobulin and do not bind peptides. They are ligands for NKG2D, which is expressed on NK cells and many T cells. MICA and MICB are expressed on endothelial cells and fibroblasts and are stress-induced in epithelial cells. | Additional information: Clone REA1076 displays negligible binding to Fc receptors.
Citations
PMID 2007850
PMID 10367903
PMID 10426993
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PE-Vio615 Excitation and Emission Spectra