IgG / PE / IS11-3B2.2.3

Citations: (2)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-119-878 (View supplier product page)
Size 100 tests in 200 µL
Price $330.00
Antigen IgG
Clone IS11-3B2.2.3
Host Mouse
Isotype IgG1,κappa
Conjugate PE
Target Species Human
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Description The Anti-IgG antibody detects all subclasses of human immunoglobulins of the IgG isotype. Clone IS11-3B2.2.3 recognizes the Fab region of IgG. IgG produced by B cells is the most abundant immunoglobulin in humans. It is expressed in a membrane-associated or a secreted form. Functions of IgGs include opsonization for phagocytosis, complement activation, feedback inhibition of B cell activation, and antibody-dependent cell-mediated cytotoxicity (ADCC).
About IgG and PE
IgG This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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PE Excitation and Emission Spectra