FluoroFinder

	Supplier	Miltenyi Biotec
	Catalog #:	130-119-312 (View supplier product page)
	Size	100 tests in 200 µL
	Price	$275.00
	Antigen	CD49a
	Clone	REA1106
	Host	Human
	Isotype	IgG1
	Conjugate	Biotin
	Target Species	Human
	Applications	FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC, Mass Cytometry
	Description	Clone REA1106 recognizes the cell adhesion molecule human CD49a, which is a 200 kDa heterodimeric integrin receptor. CD49a, also known as integrin α1, interacts with integrin β1 (CD29) to form the VLA-1 complex which functions as a receptor for collagen and laminin-1. Integrin α1 plays a role in cell-cell adhesion and T cell proliferation and is expressed by activated T cells, NK cells, neuronal cells, fibroblasts, and mesenchymal cells. \| Additional information: Clone REA1106 displays negligible binding to Fc receptors.

	CD49a	This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008]

$275.00
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CD49a / Biotin / REA1106