CD26 / APC / FR10-11G9
CD26 / APC / FR10-11G9
Citations:
(2)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-120-699 (View supplier product page) | |
Size | 100 tests in 200 µL | |
Price | $325.00 | |
Antigen | CD26 | |
Clone | FR10-11G9 | |
Host | Mouse | |
Isotype | IgG2a κ | |
Conjugate | APC | |
Target Species | Human | |
Applications | FC, IF, IHC, MICS (MACSima Imaging Cyclic Staining) | |
Description | The FR10-11G9 clone antibody recognizes CD26, a costimulatory molecule that is involved in T cell activation. CD26 is a type II transmembrane protein that acts as an ectoenzyme with prolyl oligopeptidase activity. It is widely expressed in various tissues. In the immune system CD26 is expressed on thymocytes, activated T cells, B cells, NK cells, and macrophages. |
About CD26 and APC
CD26 | The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS-CoV), and protein modeling suggests that it may play a similar role with SARS-CoV-2, the virus responsible for COVID-19. [provided by RefSeq, Apr 2020] | |
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APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
PMID 10431157 | ||
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PMID 12437097 | ||
Additional Sources |
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Reviews & Ratings
APC Excitation and Emission Spectra
$325.00
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