CD23 / PE-Vio770 / REA1068

Citations: (1)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-118-764 (View supplier product page)
Size 30 µg in 200 µL
Price $175.00
Antigen CD23
Clone REA1068
Host Human
Isotype IgG1
Conjugate PE-Vio770
Target Species Mouse
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Description Clone REA1068 recognizes mouse CD23, also known as low affinity IgE Fc receptor (FcεRII), a type II integral membrane glycoprotein. CD23 is expressed on activated B cells, follicular dendritic cells of immunized mice, on a subset of splenic dendritic cells, and mature B cells, but not on CD5+ B-1 cells. | Additional information: Clone REA1068 displays negligible binding to Fc receptors.
About CD23 and PE-Vio770
CD23 The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
PE-Vio770 PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.
Citations
Reviews & Ratings
PE-Vio770 Excitation and Emission Spectra