IL-18 R alpha / Biotin / REA1095
IL-18 R alpha / Biotin / REA1095
Citations:
(2)
Product Details
| Supplier | Miltenyi Biotec | |
|---|---|---|
| Catalog #: | 130-118-715 (View supplier product page) | |
| Size | 30 tests in 60 µL | |
| Price | $95.00 | |
| Antigen | IL-18 R alpha | |
| Clone | REA1095 | |
| Host | Human | |
| Isotype | IgG1 | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC | |
| Description | Clone REA1095 recognizes the CD218 antigen, which is also known as interleukin-18 receptor alpha (IL-18Rα) chain. IL-18 receptor is an heterodimeric receptor complex, and composed of the IL-18Rα chain and the IL-1 receptor accessory protein-like (IL-1RacPL) or IL-18Rβ chain. CD218 represents the ligand-binding chain, whereas IL-18Rβ is suggested to assist in the formation of a high affinity complex and mediates intracellular signals. IL-18R is expressed on a variety of cells including macrophages, neutrophils, natural killer (NK) cells, endothelial, and smooth muscle cells and an upregulated expression is observed on naive T cells, T helper cell type 1 (Tʜ1) cells, and B cells, in the presence IL-12. | Additional information: Clone REA1095 displays negligible binding to Fc receptors. |
Citations
| PMID 10865972 | ||
|---|---|---|
| PMID 11123287 | ||
| Additional Sources |
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Reviews & Ratings
Biotin Excitation and Emission Spectra
$95.00
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