CD131 / PE / REA193
CD131 / PE / REA193
Citations:
(1)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-118-456 (View supplier product page) | |
Size | 30 µg in 200 µL | |
Price | $75.00 | |
Antigen | CD131 | |
Clone | REA193 | |
Host | Human | |
Isotype | IgG1 | |
Conjugate | PE | |
Target Species | Mouse | |
Applications | FC | |
Description | Clone REA193 recognizes CD131, the IL-3 receptor β subunit. CD131 is a single-pass type I transmembrane protein, belongs to the cytokine receptor superfamily, and is shared by IL-3, IL-5, and GM-CSF receptors. The receptor-specific α subunits is mainly involved in ligand binding and the common β subunit, CD131, is important for transducing the signal initiated by binding of the ligands to respective receptors. | Additional information: Clone REA193 displays negligible binding to Fc receptors. | |
About CD131 and PE
CD131 | The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008] | |
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PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |
Citations
PMID 8466757 | ||
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PMID 9766809 | ||
Additional Sources |
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Reviews & Ratings
PE Excitation and Emission Spectra
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