Apolipoprotein E / HRP /
Apolipoprotein E / HRP /
Product Details
| Supplier | Aviva Systems Biology | |
|---|---|---|
| Catalog #: | OACA00134 (View supplier product page) | |
| Size | 100 μg | |
| Price | $299.00 | |
| Antigen | Apolipoprotein E | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | HRP | |
| Target Species | Mouse | |
| Applications | WB, ELISA | |
| Description | Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. |
About Apolipoprotein E and HRP
| Apolipoprotein E | The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016] |
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Citations
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