Wnt-6 / Unconjugated /
Wnt-6 / Unconjugated /
Product Details
Supplier | Aviva Systems Biology | |
---|---|---|
Catalog #: | OALA01459 (View supplier product page) | |
Size | 50 μg | |
Price | $395.00 | |
Antigen | Wnt-6 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Unconjugated | |
Target Species | Bovine, Canine, Equine, Gibbon, Gorilla, Hamster, Human, Mouse, Rabbit, Rat | |
Applications | IHC-P | |
Description | Wnt genes encode a family of secreted proteins having oncogenic potential and important roles in developmental processes. In developing mice, Wnt 6 is expressed panectodermally and in the somites, limb bud and reproductive system. The WNT6 signaling pathway has been suggested to affect human breast cancer, colon cancer, and leukemia. |
About Wnt-6 and Purified
Wnt-6 | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level. [provided by RefSeq, Jul 2008] |
---|