YL1 / Unconjugated /
YL1 / Unconjugated /
Product Details
Supplier | Aviva Systems Biology | |
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Catalog #: | OAAF02468 (View supplier product page) | |
Size | 100 μg | |
Price | $289.00 | |
Antigen | YL1 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Unconjugated | |
Target Species | Human, Mouse | |
Applications | WB, IHC, ELISA | |
Description | VPS72 Antibody (OAAF02468) Unconjugated Rabbit Polyclonal Antibody, Reacts with Human, Mouse |
About YL1 and Purified
YL1 | The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012] |
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