YL1 / Unconjugated /

Product Details
Supplier Aviva Systems Biology
Catalog #: OAAF02468 (View supplier product page)
Size 100 μg
Price $289.00
Antigen YL1
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse
Applications WB, IHC, ELISA
Description VPS72 Antibody (OAAF02468) Unconjugated Rabbit Polyclonal Antibody, Reacts with Human, Mouse
About YL1 and Purified
YL1 The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
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Purified Excitation and Emission Spectra