Neuromedin B Receptor / Unconjugated /

Product Details
Supplier Aviva Systems Biology
Catalog #: OALA01273 (View supplier product page)
Size 50 μg
Price $395.00
Antigen Neuromedin B Receptor
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Gibbon, Gorilla, Human
Applications IHC-P
Description The neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues.
About Neuromedin B Receptor and Purified
Neuromedin B Receptor This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
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Purified Excitation and Emission Spectra