CD137L / APC-Fire 750 / 5F4
CD137L / APC-Fire 750 / 5F4
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 311513 (View supplier product page) | |
| Size | 25T | |
| Price | $159.00 | |
| Antigen | CD137L | |
| Clone | 5F4 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | APC-Fire 750 | |
| Target Species | Human | |
| Applications | FC | |
| Description | APC/Fire 750 anti-human CD137L (4-1BB Ligand) |
About CD137L and APC-Fire 750
| CD137L | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided by RefSeq, Oct 2008] | |
|---|---|---|
| APC-Fire 750 | APC-Fire™ 750 from Biolegend has an excitation peak at 651 nm and an emission peak at 788 nm and is most commonly used in flow cytometry. Spectrally its similar to APC-Cy7, APC-Alexa 750 and APC-H7 |
Images
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Human T lymphoblastic leukemia cell line, Hut-78, was stained with CD137L (4-1BB Ligand, clone 5F4) APC/Fire™ 750 (filled histogram) or Mouse IgG1, κ APC/Fire™ 750 isotype control (open histogram). |
Citations
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Reviews & Ratings
APC-Fire 750 Excitation and Emission Spectra
$159.00
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