CD124 / APC / I015F8

Citations: (1)
Product Details
Supplier BioLegend
Catalog #: 144808 (View supplier product page)
Size 100 μg
Price $332.00
Antigen CD124
Clone I015F8
Host Rat
Isotype IgG2b κ
Conjugate APC
Target Species Mouse
Applications FC
Description APC anti-mouse CD124 (IL-4Ralpha)
About CD124 and APC
CD124 This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]
APC Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
Images
  CD124 APC BioLegend antibody anti target:Mouse host:Rat isotype:IgG2b κ clone:I015F8

C57BL/6 mouse splenocytes were stained with B220 PE and CD124 (clone I015F8) APC (left) or rat IgG2b, κ APC isotype control (right).

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Reviews & Ratings
APC Excitation and Emission Spectra