CD124 / APC / I015F8
CD124 / APC / I015F8
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(5)
Product Details
Supplier | BioLegend | |
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Catalog #: | 144807 (View supplier product page) | |
Size | 25 μg | |
Price | $154.00 | |
Antigen | CD124 | |
Clone | I015F8 | |
Host | Rat | |
Isotype | IgG2b κ | |
Conjugate | APC | |
Target Species | Mouse | |
Applications | FC | |
Description | APC anti-mouse CD124 (IL-4Ralpha) |
About CD124 and APC
CD124 | This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012] | |
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APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
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APC Excitation and Emission Spectra
$154.00
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