GFR alpha-1 / Unconjugated /

Product Details
Supplier Aviva Systems Biology
Catalog #: OAEG00882 (View supplier product page)
Size 100 μg
Price $340.00
Antigen GFR alpha-1
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications WB, IHC
Description GFRA1 Antibody (OAEG00882) Unconjugated Rabbit Polyclonal Antibody, Reacts with Human, Mouse, Rat
About GFR alpha-1 and Purified
GFR alpha-1 This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
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Reviews & Ratings
Purified Excitation and Emission Spectra