EGF Receptor / PE / ICR10
EGF Receptor / PE / ICR10
Product Details
Supplier | Aviva Systems Biology | |
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Catalog #: | OASA04699 (View supplier product page) | |
Size | 100 Tests | |
Price | $455.00 | |
Antigen | EGF Receptor | |
Clone | ICR10 | |
Host | Rat | |
Isotype | IgG2a | |
Conjugate | PE | |
Target Species | Human | |
Applications | FC | |
Description | RAT ANTI HUMAN EGF RECEPTOR:RPE |
About EGF Receptor and PE
EGF Receptor | The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020] | |
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PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |