Dopamine beta Hydroxylase / KLH /
Dopamine beta Hydroxylase / KLH /
Product Details
| Supplier | Aviva Systems Biology | |
|---|---|---|
| Catalog #: | OALA08716 (View supplier product page) | |
| Size | 200 μl | |
| Price | $350.00 | |
| Antigen | Dopamine beta Hydroxylase | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | KLH | |
| Target Species | Human | |
| Applications | IF, IHC-P, WB | |
| Description | DBH Antibody (OALA08716) KLH Rabbit Polyclonal Antibody, Reacts with Human |
About Dopamine beta Hydroxylase and KLH
| Dopamine beta Hydroxylase | The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. The encoded protein, expressed in neuroscretory vesicles and chromaffin granules of the adrenal medulla, catalyzes the conversion of dopamine to norepinephrine, which functions as both a hormone and as the main neurotransmitter of the sympathetic nervous system. The enzyme encoded by this gene exists exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. Mutations in this gene cause dopamine beta-hydroxylate deficiency in human patients, characterized by deficits in autonomic and cardiovascular function, including hypotension and ptosis. Polymorphisms in this gene may play a role in a variety of psychiatric disorders. [provided by RefSeq, Aug 2017] |
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Citations
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