CD11b / Unconjugated / N418
CD11b / Unconjugated / N418
Product Details
Supplier | Aviva Systems Biology | |
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Catalog #: | OASA00021 (View supplier product page) | |
Size | 25 μg | |
Price | $75.00 | |
Antigen | CD11b | |
Clone | N418 | |
Host | Hamster | |
Isotype | IgG | |
Conjugate | Unconjugated | |
Target Species | Mouse | |
Applications | IHC, FC, IP | |
Description | HAMSTER ANTI MOUSE CD11c |
About CD11b and Purified
CD11b | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
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