Bcl-6 / Unconjugated / 305CT16.3.3
Bcl-6 / Unconjugated / 305CT16.3.3
Product Details
Supplier | Aviva Systems Biology | |
---|---|---|
Catalog #: | OAAB06866 (View supplier product page) | |
Size | 100 μl | |
Price | $320.00 | |
Antigen | Bcl-6 | |
Clone | 305CT16.3.3 | |
Host | Mouse | |
Isotype | IgG1 | |
Conjugate | Unconjugated | |
Target Species | Human | |
Applications | WB, IF | |
Description | BCL6 antibody - C-terminal region (ascites) |
About Bcl-6 and Purified
Bcl-6 | The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015] |
---|