Glutamate Dehydrogenase / Unconjugated /
Glutamate Dehydrogenase / Unconjugated /
Product Details
| Supplier | Aviva Systems Biology | |
|---|---|---|
| Catalog #: | OACD03821 (View supplier product page) | |
| Size | 100 μg | |
| Price | $310.00 | |
| Antigen | Glutamate Dehydrogenase | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Mouse | |
| Applications | WB, ICC, IHC-P, IHC-Fr, ELISA | |
| Description | GLUD1 Antibody (OACD03821) Unconjugated Rabbit Polyclonal Antibody, Reacts with Mouse |
About Glutamate Dehydrogenase and Purified
| Glutamate Dehydrogenase | This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016] |
|---|
Citations
| Additional Sources |
|
|---|
