RANTES / Unconjugated /
RANTES / Unconjugated /
Product Details
| Supplier | Aviva Systems Biology | |
|---|---|---|
| Catalog #: | OACD06913 (View supplier product page) | |
| Size | 100 μg | |
| Price | $345.00 | |
| Antigen | RANTES | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Guinea Pig | |
| Applications | WB, ICC, IHC-P, IHC-Fr, ELISA | |
| Description | RANTES Antibody (OACD06913) Unconjugated Rabbit Polyclonal Antibody, Reacts with Guinea Pig |
About RANTES and Purified
| RANTES | This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013] |
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Citations
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