PSMB10 / Unconjugated /
PSMB10 / Unconjugated /
Product Details
| Supplier | Aviva Systems Biology | |
|---|---|---|
| Catalog #: | OAAB08845 (View supplier product page) | |
| Size | 400 μl | |
| Price | $320.00 | |
| Antigen | PSMB10 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | Ig | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | WB | |
| Description | PSMB10 antibody - C-terminal region |
About PSMB10 and Purified
| PSMB10 | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq, Jul 2008] |
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Citations
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